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Programmed Death 1 Regulates Memory Phenotype CD4 T Cell Accumulation, Inhibits Expansion of the Effector Memory Phenotype Subset and Modulates Production of Effector Cytokines

Memory phenotype CD4 T cells are found in normal mice and arise through response to environmental antigens or homeostatic mechanisms. The factors that regulate the homeostasis of memory phenotype CD4 cells are not clear. In the present study we demonstrate that there is a marked accumulation of memo...

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Detalles Bibliográficos
Autores principales: Charlton, Joanna J., Tsoukatou, Debbie, Mamalaki, Clio, Chatzidakis, Ioannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372408/
https://www.ncbi.nlm.nih.gov/pubmed/25803808
http://dx.doi.org/10.1371/journal.pone.0119200