A Novel Triple Repeat Mutant Tau Transgenic Model That Mimics Aspects of Pick’s Disease and Fronto-Temporal Tauopathies

Tauopathies are a group of disorders leading to cognitive and behavioral impairment in the aging population. While four-repeat (4R) Tau is more abundant in corticobasal degeneration, progressive supranuclear palsy, and Alzheimer’s disease, three-repeat (3R) Tau is the most abundant splice, in Pick&#...

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Detalles Bibliográficos
Autores principales: Rockenstein, Edward, Overk, Cassia R., Ubhi, Kiren, Mante, Michael, Patrick, Christina, Adame, Anthony, Bisquert, Alejandro, Trejo-Morales, Margarita, Spencer, Brian, Masliah, Eliezer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372415/
https://www.ncbi.nlm.nih.gov/pubmed/25803611
http://dx.doi.org/10.1371/journal.pone.0121570

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372415/
https://www.ncbi.nlm.nih.gov/pubmed/25803611
http://dx.doi.org/10.1371/journal.pone.0121570

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