IKK2 Inhibition Using TPCA-1-Loaded PLGA Microparticles Attenuates Laser-Induced Choroidal Neovascularization and Macrophage Recruitment

The inhibition of NF-κB by genetic deletion or pharmacological inhibition of IKK2 significantly reduces laser-induced choroid neovascularization (CNV). To achieve a sustained and controlled intraocular release of a selective and potent IKK2 inhibitor, 2-[(aminocarbonyl)amino]-5-(4-fluorophenyl)-3-th...

Descripción completa

Detalles Bibliográficos
Autores principales: Gaddipati, Subhash, Lu, Qingxian, Kasetti, Ramesh Babu, Miller, M. Clarke, Lu, Qingjun, Trent, John O., Kaplan, Henry J., Li, Qiutang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372421/
https://www.ncbi.nlm.nih.gov/pubmed/25803615
http://dx.doi.org/10.1371/journal.pone.0121185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372421/
https://www.ncbi.nlm.nih.gov/pubmed/25803615
http://dx.doi.org/10.1371/journal.pone.0121185

Ejemplares similares