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MTHFR 677C>T Polymorphism and the Risk of Breast Cancer: Evidence from an Original Study and Pooled Data for 28031 Cases and 31880 Controls

BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) acts at an important metabolic point in the regulation of cellular methylation reaction. It assists in the conversion of 5, 10-methylenetetrahydrofolate to 5-methyltetrahydrofolate. The latter aids in remethylation of homocysteine to de novo me...

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Detalles Bibliográficos
Autores principales: Pooja, Singh, Carlus, Justin, Sekhar, Deepa, Francis, Amirtharaj, Gupta, Nishi, Konwar, Rituraj, Kumar, Sandeep, Kumar, Surender, Thangaraj, Kumarasamy, Rajender, Singh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372432/
https://www.ncbi.nlm.nih.gov/pubmed/25803740
http://dx.doi.org/10.1371/journal.pone.0120654