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Btk29A-Mediated Tyrosine Phosphorylation of Armadillo/β-Catenin Promotes Ring Canal Growth in Drosophila Oogenesis

Drosophila Btk29A is the ortholog of mammalian Btk, a Tec family nonreceptor tyrosine kinase whose deficit causes X-linked agammaglobulinemia in humans. The Btk29A(ficP) mutation induces multiple abnormalities in oogenesis, including the growth arrest of ring canals, large intercellular bridges that...

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Detalles Bibliográficos
Autores principales: Hamada-Kawaguchi, Noriko, Nishida, Yasuyoshi, Yamamoto, Daisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372500/
https://www.ncbi.nlm.nih.gov/pubmed/25803041
http://dx.doi.org/10.1371/journal.pone.0121484