Streptococcus pneumoniae Induces Autophagy through the Inhibition of the PI3K-I/Akt/mTOR Pathway and ROS Hypergeneration in A549 Cells

The present study focused on the action mechanism of S. pneumoniae (Sp) in inducing autophagy in human alveolar epithelial cells. Sp, a gram-positive extracellular bacterium, activates autophagy with considerably increased microtuble-associated protein light chain 3 (LC3) punctation in A549 cells. T...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Pu, Shi, Jing, He, Qiao, Hu, Qin, Wang, Yun Ying, Zhang, Li Jun, Chan, Wai Ting, Chen, Wei-Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372526/
https://www.ncbi.nlm.nih.gov/pubmed/25803050
http://dx.doi.org/10.1371/journal.pone.0122753

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372526/
https://www.ncbi.nlm.nih.gov/pubmed/25803050
http://dx.doi.org/10.1371/journal.pone.0122753

Ejemplares similares