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Splice Variants of Activation Induced Deaminase (AID) Do Not Affect the Efficiency of Class Switch Recombination in Murine CH12F3 Cells
Activation Induced Deaminase (AID) triggers the antigen-driven antibody diversification processes through its ability to edit DNA. AID dependent DNA damage is also the cause of genetic alterations often found in mature B cell tumors. A number of splice variants of AID have been identified, for which...
Autores principales: | Sala, Cesare, Mattiuz, Giorgio, Pietrobono, Silvia, Chicca, Andrea, Conticello, Silvestro G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372541/ https://www.ncbi.nlm.nih.gov/pubmed/25803053 http://dx.doi.org/10.1371/journal.pone.0121719 |
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