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Thrombospondin1 Deficiency Attenuates Obesity-Associated Microvascular Complications in ApoE-/- Mice

Obesity is associated with insulin resistance and the increased development of vascular complications. Previously, we have demonstrated that thrombospondin1 (TSP1) regulates macrophage function and contributes to obesity associated inflammation and insulin resistance. However, the role of TSP1 in th...

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Detalles Bibliográficos
Autores principales: Maimaitiyiming, Hasiyeti, Clemons, Kate, Zhou, Qi, Norman, Heather, Wang, Shuxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372557/
https://www.ncbi.nlm.nih.gov/pubmed/25803585
http://dx.doi.org/10.1371/journal.pone.0121403