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β-Arrestin Regulates Estradiol Membrane-Initiated Signaling in Hypothalamic Neurons
Estradiol (E2) action in the nervous system is the result of both direct nuclear and membrane-initiated signaling (EMS). E2 regulates membrane estrogen receptor-α (ERα) levels through opposing mechanisms of EMS-mediated trafficking and internalization. While ß-arrestin-mediated mERα internalization...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372564/ https://www.ncbi.nlm.nih.gov/pubmed/25803606 http://dx.doi.org/10.1371/journal.pone.0120530 |