Cargando…

β-Arrestin Regulates Estradiol Membrane-Initiated Signaling in Hypothalamic Neurons

Estradiol (E2) action in the nervous system is the result of both direct nuclear and membrane-initiated signaling (EMS). E2 regulates membrane estrogen receptor-α (ERα) levels through opposing mechanisms of EMS-mediated trafficking and internalization. While ß-arrestin-mediated mERα internalization...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wong, Angela M., Abrams, Matthew C., Micevych, Paul E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372564/ https://www.ncbi.nlm.nih.gov/pubmed/25803606 http://dx.doi.org/10.1371/journal.pone.0120530

Ejemplares similares

Membrane-Initiated Estradiol Signaling Regulating Sexual Receptivity
por: Micevych, Paul E., et al.
Publicado: (2011)

Estradiol Modulates Translocator Protein (TSPO) and Steroid Acute Regulatory Protein (StAR) via Protein Kinase A (PKA) Signaling in Hypothalamic Astrocytes
por: Chen, Claire, et al.
Publicado: (2014)

Sex differences in hypothalamic astrocyte response to estradiol stimulation
por: Kuo, John, et al.
Publicado: (2010)

β-arrestin mediates communication between plasma membrane and intracellular GPCRs to regulate signaling
por: DeNies, Maxwell S., et al.
Publicado: (2020)

Neuroprotective Effects of 17β-Estradiol Rely on Estrogen Receptor Membrane Initiated Signals
por: Fiocchetti, Marco, et al.
Publicado: (2012)

Membrane phosphoinositides regulate GPCR-β-arrestin complex assembly and dynamics
por: Janetzko, John, et al.
Publicado: (2022)

Distinct and Shared Roles of β-Arrestin-1 and β-Arrestin-2 on the Regulation of C3a Receptor Signaling in Human Mast Cells
por: Vibhuti, Arpana, et al.
Publicado: (2011)

Hypothalamic Astrocyte Development and Physiology for Neuroprogesterone Induction of the Luteinizing Hormone Surge
por: Sinchak, Kevin, et al.
Publicado: (2020)

Estradiol Regulates Brown Adipose Tissue Thermogenesis via Hypothalamic AMPK
por: Martínez de Morentin, Pablo B., et al.
Publicado: (2014)

Estradiol regulates leptin sensitivity to control feeding via hypothalamic Cited1
por: González-García, Ismael, et al.
Publicado: (2023)

Hypothalamic neuronal outputs transmit sensorimotor signals at the onset of locomotor initiation
por: Martianova, Ekaterina, et al.
Publicado: (2023)

The Role of β-Arrestin Proteins in Organization of Signaling and Regulation of the AT1 Angiotensin Receptor
por: Turu, Gábor, et al.
Publicado: (2019)

17β-estradiol promotes acute refeeding in hungry mice via membrane-initiated ERα signaling
por: Yu, Kaifan, et al.
Publicado: (2020)

SAT-424 Estrogen-Responsiveness of Female Mouse Hypothalamic Astrocytes: A Developmental Study
por: Mohr, Margaret, et al.
Publicado: (2019)

Membrane estrogen signaling in female reproduction and motivation
por: Johnson, Caroline S., et al.
Publicado: (2022)

ACKR4 Recruits GRK3 Prior to β-Arrestins but Can Scavenge Chemokines in the Absence of β-Arrestins
por: Matti, Christoph, et al.
Publicado: (2020)

Estradiol Regulates Energy Balance by Ameliorating Hypothalamic Ceramide-Induced ER Stress
por: González-García, Ismael, et al.
Publicado: (2018)

LSD-stimulated behaviors in mice require β-arrestin 2 but not β-arrestin 1
por: Rodriguiz, Ramona M., et al.
Publicado: (2021)

Arrestins: ubiquitous regulators of cellular signaling pathways
por: Gurevich, Eugenia V, et al.
Publicado: (2006)

GPCR Signaling Regulation: The Role of GRKs and Arrestins
por: Gurevich, Vsevolod V., et al.
Publicado: (2019)

Norepinephrine Regulation of Ventromedial Hypothalamic Nucleus Metabolic-Sensory Neuron 5′-AMP-Activated Protein Kinase Activity: Impact of Estradiol
por: Mahmood, A. S. M. Hasan, et al.
Publicado: (2020)

β-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation
por: Ahn, Seungkirl, et al.
Publicado: (2009)

RNA-sequencing of AVPV and ARH reveals vastly different temporal and transcriptomic responses to estradiol in the female rat hypothalamus
por: Mohr, Margaret A., et al.
Publicado: (2021)

17α‐estradiol acts through hypothalamic pro‐opiomelanocortin expressing neurons to reduce feeding behavior
por: Steyn, Frederik J., et al.
Publicado: (2017)

Estradiol-dependent axogenesis and Ngn3 expression are determined by XY sex chromosome complement in hypothalamic neurons
por: Cisternas, Carla Daniela, et al.
Publicado: (2020)

GPR54 Regulates ERK1/2 Activity and Hypothalamic Gene Expression in a Gα(q/11) and β-Arrestin-Dependent Manner
por: Szereszewski, Jacob M., et al.
Publicado: (2010)

Molecular mechanisms of fentanyl mediated β-arrestin biased signaling
por: de Waal, Parker W., et al.
Publicado: (2020)

Scaffolding of Mitogen-Activated Protein Kinase Signaling by β-Arrestins
por: Kim, Kiae, et al.
Publicado: (2022)

Signal transduction at GPCRs: Allosteric activation of the ERK MAPK by β-arrestin
por: Kahsai, Alem W., et al.
Publicado: (2023)

Beneficial metabolic role of β-arrestin-1 expressed by AgRP neurons
por: Pydi, Sai P., et al.
Publicado: (2020)

Cannabinoid receptor type 1 (CB(1)R) inhibits hypothalamic leptin signaling via β-arrestin1 in complex with TC-PTP and STAT3
por: Szanda, Gergő, et al.
Publicado: (2023)

Discrete GPCR-triggered endocytic modes enable β-arrestins to flexibly regulate cell signaling
por: Barsi-Rhyne, Benjamin, et al.
Publicado: (2022)

Estradiol Meets Notch Signaling in Developing Neurons
por: Arevalo, María Angeles, et al.
Publicado: (2011)

Estradiol Activates β-Catenin Dependent Transcription in Neurons
por: Varea, Olga, et al.
Publicado: (2009)

β-arrestin-2 regulates NMDA receptor function in spinal lamina II neurons and duration of persistent pain
por: Chen, Gang, et al.
Publicado: (2016)

Improved Split TEV GPCR β-arrestin-2 Recruitment Assays via Systematic Analysis of Signal Peptide and β-arrestin Binding Motif Variants
por: Wu, Yuxin, et al.
Publicado: (2022)

Not all arrestins are created equal: Therapeutic implications of the functional diversity of the β-arrestins in the heart
por: Lymperopoulos, Anastasios, et al.
Publicado: (2019)

c-Src Regulates Akt Signaling in Response to Ghrelin via β-Arrestin Signaling-Independent and -Dependent Mechanisms
por: Lodeiro, Maria, et al.
Publicado: (2009)

Catalytic activation of β-arrestin by GPCRs
por: Eichel, Kelsie, et al.
Publicado: (2018)

β-arrestin1 at the cross-road of endothelin-1 signaling in cancer
por: Rosanò, Laura, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_krupnih440t239ub624djgoho7