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The Nicotinic Receptor Alpha7 Impacts the Mouse Lung Response to LPS through Multiple Mechanisms

The nicotinic acetylcholine receptor alpha7 (α7) is expressed by neuronal and non-neuronal cells throughout the body. We examined the mechanisms of the lung inflammatory response to intranasal (i.n.) lipopolysaccharide (LPS) regulated by α7. This was done in mice using homologous recombination to in...

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Detalles Bibliográficos
Autores principales: Enioutina, Elena Y., Myers, Elizabeth J., Tvrdik, Petr, Hoidal, John R., Rogers, Scott W., Gahring, Lorise C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372581/
https://www.ncbi.nlm.nih.gov/pubmed/25803612
http://dx.doi.org/10.1371/journal.pone.0121128