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The Nicotinic Receptor Alpha7 Impacts the Mouse Lung Response to LPS through Multiple Mechanisms
The nicotinic acetylcholine receptor alpha7 (α7) is expressed by neuronal and non-neuronal cells throughout the body. We examined the mechanisms of the lung inflammatory response to intranasal (i.n.) lipopolysaccharide (LPS) regulated by α7. This was done in mice using homologous recombination to in...
Autores principales: | Enioutina, Elena Y., Myers, Elizabeth J., Tvrdik, Petr, Hoidal, John R., Rogers, Scott W., Gahring, Lorise C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372581/ https://www.ncbi.nlm.nih.gov/pubmed/25803612 http://dx.doi.org/10.1371/journal.pone.0121128 |
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