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Cadherin Expression, Vectorial Active Transport, and Metallothionein Isoform 3 Mediated EMT/MET Responses in Cultured Primary and Immortalized Human Proximal Tubule Cells

BACKGROUND: Cultures of human proximal tubule cells have been widely utilized to study the role of EMT in renal disease. The goal of this study was to define the role of growth media composition on classic EMT responses, define the expression of E- and N-cadherin, and define the functional epitope o...

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Detalles Bibliográficos
Autores principales: Slusser, Andrea, Bathula, Chandra S., Sens, Donald A., Somji, Seema, Sens, Mary Ann, Zhou, Xu Dong, Garrett, Scott H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372585/
https://www.ncbi.nlm.nih.gov/pubmed/25803827
http://dx.doi.org/10.1371/journal.pone.0120132