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Autonomously Folding Protein Fragments Reveal Differences in the Energy Landscapes of Homologous RNases H
An important approach to understanding how a protein sequence encodes its energy landscape is to compare proteins with different sequences that fold to the same general native structure. In this work, we compare E. coli and T. thermophilus homologs of the protein RNase H. Using protein fragments, we...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372590/ https://www.ncbi.nlm.nih.gov/pubmed/25803034 http://dx.doi.org/10.1371/journal.pone.0119640 |