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Smyd1 Facilitates Heart Development by Antagonizing Oxidative and ER Stress Responses

Smyd1/Bop is an evolutionary conserved histone methyltransferase previously shown by conventional knockout to be critical for embryonic heart development. To further explore the mechanism(s) in a cell autonomous context, we conditionally ablated Smyd1 in the first and second heart fields of mice usi...

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Detalles Bibliográficos
Autores principales: Rasmussen, Tara L., Ma, Yanlin, Park, Chong Yon, Harriss, June, Pierce, Stephanie A., Dekker, Joseph D., Valenzuela, Nicolas, Srivastava, Deepak, Schwartz, Robert J., Stewart, M. David, Tucker, Haley O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372598/
https://www.ncbi.nlm.nih.gov/pubmed/25803368
http://dx.doi.org/10.1371/journal.pone.0121765