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Characterization of G protein coupling mediated by the conserved D134(3.49) of DRY motif, M241(6.34), and F251(6.44) residues on human CXCR1

CXCR1, a receptor for interleukin-8 (IL-8), plays an important role in defending against pathogen invasion during neutrophil-mediated innate immune response. Human CXCR1 is a G protein-coupled receptor (GPCR) with its characteristic seven transmembrane domains (TMs). Functional and structural analys...

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Detalles Bibliográficos
Autores principales: Han, Xinbing, Feng, Yan, Chen, Xinhua, Gerard, Craig, Boisvert, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372616/
https://www.ncbi.nlm.nih.gov/pubmed/25834784
http://dx.doi.org/10.1016/j.fob.2015.03.001