Role of P2X7 and P2Y(2) receptors on α-secretase-dependent APP processing: Control of amyloid plaques formation “in vivo” by P2X7 receptor

Amyloid precursor protein (APP) is expressed in a large variety of neural and non-neural cells. The balance between non-pathogenic and pathologic forms of APP processing, mediated by α-secretase and β-secretase respectively, remains a crucial step to understand β-amyloid, Aβ42 peptide, formation and...

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Detalles Bibliográficos
Autores principales: Miras-Portugal, M. Teresa, Diaz-Hernandez, Juan I., Gomez-Villafuertes, Rosa, Diaz-Hernandez, Miguel, Artalejo, Antonio R., Gualix, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2015
Materias:
Mini Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372621/
https://www.ncbi.nlm.nih.gov/pubmed/25848496
http://dx.doi.org/10.1016/j.csbj.2015.02.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372621/
https://www.ncbi.nlm.nih.gov/pubmed/25848496
http://dx.doi.org/10.1016/j.csbj.2015.02.005

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