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G-231A and G+70C Polymorphisms of Endothelin Receptor Type-A Gene could Affect the Psoriasis Area and Severity Index Score and Endothelin 1 Levels

BACKGROUND: The etiopathogenesis of psoriasis has not been clearly elucidated although the role of chronic inflammation, imbalance between pro- and anti-inflammatory cytokines, and many immunological events have been established. Endothelin 1 (EDN1) and endothelin receptor type-A (EDNRA) are implica...

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Detalles Bibliográficos
Autores principales: Okan, Gökhan, Yıldız, Zeynep, Gökdemir, Gonca, Yorulmaz, Eda, Vural, Pervin, Doğru-Abbasoğlu, Semra, Uysal, Müjdat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372930/
https://www.ncbi.nlm.nih.gov/pubmed/25814726
http://dx.doi.org/10.4103/0019-5154.152561