Cargando…
A putative N-terminal nuclear export sequence is sufficient for Mps1 nuclear exclusion during interphase
BACKGROUND: Mps1, an essential component of the mitotic checkpoint, is also an important interphase regulator and has roles in DNA damage response, cytokinesis and centrosome duplication. Mps1 predominantly resides in the cytoplasm and relocates into the nucleus at the late G2 phase. So far, the mec...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373099/ https://www.ncbi.nlm.nih.gov/pubmed/25886724 http://dx.doi.org/10.1186/s12860-015-0048-6 |