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High fat diet-induced liver steatosis promotes an increase in liver mitochondrial biogenesis in response to hypoxia
Mitochondrial DNA (mtDNA) copy number plays a key role in the pathophysiology of metabolic syndrome-related phenotypes, but its role in non-alcoholic fatty liver disease (NAFLD) is not well understood. We evaluated the molecular mechanisms that may be involved in the regulation of liver mtDNA conten...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373333/ https://www.ncbi.nlm.nih.gov/pubmed/20629985 http://dx.doi.org/10.1111/j.1582-4934.2010.01128.x |