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High fat diet-induced liver steatosis promotes an increase in liver mitochondrial biogenesis in response to hypoxia

Mitochondrial DNA (mtDNA) copy number plays a key role in the pathophysiology of metabolic syndrome-related phenotypes, but its role in non-alcoholic fatty liver disease (NAFLD) is not well understood. We evaluated the molecular mechanisms that may be involved in the regulation of liver mtDNA conten...

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Detalles Bibliográficos
Autores principales:	Carabelli, Julieta, Burgueño, Adriana L, Rosselli, Maria Soledad, Gianotti, Tomas Fernández, Lago, Nestor R, Pirola, Carlos J, Sookoian, Silvia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2011
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373333/ https://www.ncbi.nlm.nih.gov/pubmed/20629985 http://dx.doi.org/10.1111/j.1582-4934.2010.01128.x

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