Promoter hypomethylation up-regulates CD147 expression through increasing Sp1 binding and associates with poor prognosis in human hepatocellular carcinoma

CD147 is a transmembrane glycoprotein overexpressed in human hepatocellular carcinoma (HCC) which could promote HCC progression and metastasis. Promoter methylation is one of the most important processes in gene regulation. In this study, we aim to investigate CD147 promoter methylation status and t...

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Detalles Bibliográficos
Autores principales: Kong, Ling-Min, Liao, Cheng-Gong, Chen, Liang, Yang, Hu-Shan, Zhang, Si-He, Zhang, Zheng, Bian, Hui-Jie, Xing, Jin-Liang, Chen, Zhi-Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373337/
https://www.ncbi.nlm.nih.gov/pubmed/20629990
http://dx.doi.org/10.1111/j.1582-4934.2010.01124.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373337/
https://www.ncbi.nlm.nih.gov/pubmed/20629990
http://dx.doi.org/10.1111/j.1582-4934.2010.01124.x

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