Cargando…

Promoter hypomethylation up-regulates CD147 expression through increasing Sp1 binding and associates with poor prognosis in human hepatocellular carcinoma

CD147 is a transmembrane glycoprotein overexpressed in human hepatocellular carcinoma (HCC) which could promote HCC progression and metastasis. Promoter methylation is one of the most important processes in gene regulation. In this study, we aim to investigate CD147 promoter methylation status and t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kong, Ling-Min, Liao, Cheng-Gong, Chen, Liang, Yang, Hu-Shan, Zhang, Si-He, Zhang, Zheng, Bian, Hui-Jie, Xing, Jin-Liang, Chen, Zhi-Nan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2011
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373337/ https://www.ncbi.nlm.nih.gov/pubmed/20629990 http://dx.doi.org/10.1111/j.1582-4934.2010.01124.x

Ejemplares similares

Hypomethylation of 111 Probes Predicts Poor Prognosis for Glioblastoma
por: Chen, Qi, et al.
Publicado: (2019)

Doxycycline Inducible Chimeric Antigen Receptor T Cells Targeting CD147 for Hepatocellular Carcinoma Therapy
por: Zhang, Ren-Yu, et al.
Publicado: (2019)

Active demethylation upregulates CD147 expression promoting non-small cell lung cancer invasion and metastasis
por: Liao, Cheng-Gong, et al.
Publicado: (2022)

Role of CD147 in the development and diagnosis of hepatocellular carcinoma
por: Huang, Defa, et al.
Publicado: (2023)

CD147 functions as the signaling receptor for extracellular divalent copper in hepatocellular carcinoma cells
por: Ding, Pengfei, et al.
Publicado: (2017)

Basolateral CD147 induces hepatocyte polarity loss by E‐cadherin ubiquitination and degradation in hepatocellular carcinoma progress
por: Lu, Meng, et al.
Publicado: (2018)

CD147 promotes collective invasion through cathepsin B in hepatocellular carcinoma
por: Wang, Shi-Jie, et al.
Publicado: (2020)

Overexpression of Epcam and CD133 Correlates with Poor Prognosis in Dual-phenotype Hepatocellular Carcinoma
por: Zhang, Jie, et al.
Publicado: (2020)

CD147 reinforces [Ca(2+)](i) oscillations and promotes oncogenic progression in hepatocellular carcinoma
por: Tang, Juan, et al.
Publicado: (2015)

Monocarboxylate transporter 4 (MCT4) and CD147 overexpression is associated with poor prognosis in prostate cancer
por: Pértega-Gomes, Nelma, et al.
Publicado: (2011)

Full-length soluble CD147 promotes MMP-2 expression and is a potential serological marker in detection of hepatocellular carcinoma
por: Wu, Jiao, et al.
Publicado: (2014)

CD147 contributes to SARS-CoV-2-induced pulmonary fibrosis
por: Wu, Jiao, et al.
Publicado: (2022)

Efficacy of anti-CD147 chimeric antigen receptors targeting hepatocellular carcinoma
por: Tseng, Hsiang-chi, et al.
Publicado: (2020)

Upregulation of liver kinase B1 predicts poor prognosis in hepatocellular carcinoma
por: Tan, Xiaolong, et al.
Publicado: (2018)

Embryonic Morphogen Nodal Is Associated with Progression and Poor Prognosis of Hepatocellular Carcinoma
por: Chen, Jing, et al.
Publicado: (2014)

Hypomethylation of CNTFRα is associated with proliferation and poor prognosis in lower grade gliomas
por: Fan, Kun, et al.
Publicado: (2017)

Deficiency of CD147 Attenuated Non-alcoholic Steatohepatitis Progression in an NLRP3-Dependent Manner
por: Zhang, Tian, et al.
Publicado: (2020)

HAb18G/CD147 Regulates Vinculin-Mediated Focal Adhesion and Cytoskeleton Organization in Cultured Human Hepatocellular Carcinoma Cells
por: Liang, Qiang, et al.
Publicado: (2014)

CD147/Basigin: a Warburg oncogene in hepatocellular carcinoma?
por: Calvisi, Diego Francesco
Publicado: (2016)

CD147 Promotes CXCL1 Expression and Modulates Liver Fibrogenesis
por: Shi, Wen-Pu, et al.
Publicado: (2018)

Three hypomethylated genes were associated with poor overall survival in pancreatic cancer patients
por: Chen, Huiming, et al.
Publicado: (2019)

Targeting CD147 for T to NK Lineage Reprogramming and Tumor Therapy
por: Geng, Jie-Jie, et al.
Publicado: (2017)

Co-expression of Lewis y antigen and CD147 in epithelial ovarian cancer is correlated with malignant progression and poor prognosis
por: Liu, Juanjuan, et al.
Publicado: (2019)

TMEM147 is a novel biomarker for diagnosis and prognosis of hepatocellular carcinoma
por: Fan, Wen-Jie, et al.
Publicado: (2023)

Expression patterns of cluster of differentiation 147 impact the prognosis of hepatocellular carcinoma
por: Xu, Yun-Ji, et al.
Publicado: (2023)

System analysis of the regulation of the immune response by CD147 and FOXC1 in cancer cell lines
por: Shang, Yu-Kui, et al.
Publicado: (2018)

Blockade of Macrophage CD147 Protects Against Foam Cell Formation in Atherosclerosis
por: Lv, Jian-Jun, et al.
Publicado: (2021)

Involvement of HAb18G/CD147 in T cell activation and immunological synapse formation
por: Hu, Jinsong, et al.
Publicado: (2010)

Role of MMP-2 and CD147 in kidney fibrosis
por: Cheng, Zhengyuan, et al.
Publicado: (2022)

CD146 promotes metastasis and predicts poor prognosis of hepatocellular carcinoma
por: Jiang, Guoqing, et al.
Publicado: (2016)

CD147 blockade as a potential and novel treatment of graft rejection
por: Luan, Jing, et al.
Publicado: (2017)

Activation of TGF-β1-CD147 positive feedback loop in hepatic stellate cells promotes liver fibrosis
por: Li, Hai-Yan, et al.
Publicado: (2015)

IL-10 promoter hypomethylation is associated with increased IL-10 expression and poor survival in hepatocellular carcinoma
por: Zhang, Xianjing, et al.
Publicado: (2019)

Importance of N-Glycosylation on CD147 for Its Biological Functions
por: Bai, Yang, et al.
Publicado: (2014)

Making cancer fat: reprogramming of lipid metabolism by CD147 in hepatocellular carcinoma
por: Ju, Hye-Lim, et al.
Publicado: (2016)

CD147 Expression in Human Gastric Cancer Is Associated with Tumor Recurrence and Prognosis
por: Chu, Dake, et al.
Publicado: (2014)

LINE-1 hypomethylation in gastric cancer, detected by bisulfite pyrosequencing, is associated with poor prognosis
por: Shigaki, Hironobu, et al.
Publicado: (2012)

Clinical Significance of CD147 in Children with Inflammatory Bowel Disease
por: Wang, Hongli, et al.
Publicado: (2020)

CD147 expression was positively linked to aggressiveness and worse prognosis of gastric cancer: a meta and bioinformatics analysis
por: Zheng, Hua-Chuan, et al.
Publicado: (2017)

CD147 promotes cell motility via upregulation of p190-B RhoGAP in hepatocellular carcinoma
por: Chen, Ruo, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_e4k2pmvnfcm6gmp22h5aab3j4p