New perspectives in signaling mediated by receptors coupled to stimulatory G protein: the emerging significance of cAMP efflux and extracellular cAMP-adenosine pathway

G protein-coupled receptors (GPCRs) linked to stimulatory G (Gs) proteins (GsPCRs) mediate increases in intracellular cyclic AMP as consequence of activation of nine adenylyl cyclases , which differ considerably in their cellular distribution and activation mechanisms. Once produced, cyclic AMP may...

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Detalles Bibliográficos
Autores principales: Godinho, Rosely O., Duarte, Thiago, Pacini, Enio S. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373373/
https://www.ncbi.nlm.nih.gov/pubmed/25859216
http://dx.doi.org/10.3389/fphar.2015.00058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373373/
https://www.ncbi.nlm.nih.gov/pubmed/25859216
http://dx.doi.org/10.3389/fphar.2015.00058

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