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Nox2 and Nox4 mediate tumour necrosis factor-α-induced ventricular remodelling in mice
Reactive oxygen species (ROS) and pro-inflammatory cytokines are crucial in ventricular remodelling, such as inflammation-associated myocarditis. We previously reported that tumour necrosis factor-α (TNF-α)-induced ROS in human aortic smooth muscle cells is mediated by NADPH oxidase subunit Nox4. In...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373429/ https://www.ncbi.nlm.nih.gov/pubmed/21251215 http://dx.doi.org/10.1111/j.1582-4934.2011.01261.x |