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Insights into the fate of the N-terminal amyloidogenic polypeptide of ApoA-I in cultured target cells

Apolipoprotein A-I (ApoA-I) is an extracellular lipid acceptor, whose role in cholesterol efflux and high-density lipoprotein formation is mediated by ATP-binding cassette transporter A1 (ABCA1). Nevertheless, some ApoA-I variants are associated to systemic forms of amyloidosis, characterized by ext...

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Detalles Bibliográficos
Autores principales: Arciello, Angela, De Marco, Nadia, Del Giudice, Rita, Guglielmi, Fulvio, Pucci, Piero, Relini, Annalisa, Monti, Daria Maria, Piccoli, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373434/
https://www.ncbi.nlm.nih.gov/pubmed/21306558
http://dx.doi.org/10.1111/j.1582-4934.2011.01271.x