Aberrant methylation and associated transcriptional mobilization of Alu elements contributes to genomic instability in hypoxia

Hypoxia is an integral part of tumorigenesis and contributes extensively to the neoplastic phenotype including drug resistance and genomic instability. It has also been reported that hypoxia results in global demethylation. Because a majority of the cytosine-phosphate-guanine (CpG) islands are found...

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Detalles Bibliográficos
Autores principales: Pal, Arnab, Srivastava, Tapasya, Sharma, Manish K, Mehndiratta, Mohit, Das, Prerna, Sinha, Subrata, Chattopadhyay, Parthaprasad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373486/
https://www.ncbi.nlm.nih.gov/pubmed/19508390
http://dx.doi.org/10.1111/j.1582-4934.2009.00792.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373486/
https://www.ncbi.nlm.nih.gov/pubmed/19508390
http://dx.doi.org/10.1111/j.1582-4934.2009.00792.x

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