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Schip1 Is a Novel Podocyte Foot Process Protein that Mediates Actin Cytoskeleton Rearrangements and Forms a Complex with Nherf2 and Ezrin

BACKGROUND: Podocyte foot process effacement accompanied by actin cytoskeleton rearrangements is a cardinal feature of many progressive human proteinuric diseases. RESULTS: By microarray profiling of mouse glomerulus, SCHIP1 emerged as one of the most highly enriched transcripts. We detected Schip1...

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Detalles Bibliográficos
Autores principales: Perisic, Ljubica, Rodriguez, Patricia Q., Hultenby, Kjell, Sun, Ying, Lal, Mark, Betsholtz, Christer, Uhlén, Mathias, Wernerson, Annika, Hedin, Ulf, Pikkarainen, Timo, Tryggvason, Karl, Patrakka, Jaakko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373682/
https://www.ncbi.nlm.nih.gov/pubmed/25807495
http://dx.doi.org/10.1371/journal.pone.0122067