Tumor Cells Switch to Mitochondrial Oxidative Phosphorylation under Radiation via mTOR-Mediated Hexokinase II Inhibition - A Warburg-Reversing Effect

A unique feature of cancer cells is to convert glucose into lactate to produce cellular energy, even under the presence of oxygen. Called aerobic glycolysis [The Warburg Effect] it has been extensively studied and the concept of aerobic glycolysis in tumor cells is generally accepted. However, it is...

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Detalles Bibliográficos
Autores principales: Lu, Chung-Ling, Qin, Lili, Liu, Hsin-Chen, Candas, Demet, Fan, Ming, Li, Jian Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373728/
https://www.ncbi.nlm.nih.gov/pubmed/25807077
http://dx.doi.org/10.1371/journal.pone.0121046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373728/
https://www.ncbi.nlm.nih.gov/pubmed/25807077
http://dx.doi.org/10.1371/journal.pone.0121046

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