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Tumor Cells Switch to Mitochondrial Oxidative Phosphorylation under Radiation via mTOR-Mediated Hexokinase II Inhibition - A Warburg-Reversing Effect
A unique feature of cancer cells is to convert glucose into lactate to produce cellular energy, even under the presence of oxygen. Called aerobic glycolysis [The Warburg Effect] it has been extensively studied and the concept of aerobic glycolysis in tumor cells is generally accepted. However, it is...
Autores principales: | Lu, Chung-Ling, Qin, Lili, Liu, Hsin-Chen, Candas, Demet, Fan, Ming, Li, Jian Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373728/ https://www.ncbi.nlm.nih.gov/pubmed/25807077 http://dx.doi.org/10.1371/journal.pone.0121046 |
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