A Cascade of Iron-Containing Proteins Governs the Genetic Iron Starvation Response to Promote Iron Uptake and Inhibit Iron Storage in Fission Yeast

Iron is an essential cofactor, but it is also toxic at high levels. In Schizosaccharomyces pombe, the sensor glutaredoxin Grx4 guides the activity of the repressors Php4 and Fep1 to mediate a complex transcriptional response to iron deprivation: activation of Php4 and inactivation of Fep1 leads to i...

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Detalles Bibliográficos
Autores principales: Encinar del Dedo, Javier, Gabrielli, Natalia, Carmona, Mercè, Ayté, José, Hidalgo, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373815/
https://www.ncbi.nlm.nih.gov/pubmed/25806539
http://dx.doi.org/10.1371/journal.pgen.1005106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373815/
https://www.ncbi.nlm.nih.gov/pubmed/25806539
http://dx.doi.org/10.1371/journal.pgen.1005106

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