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Recovery of Aging-Related Size Increase of Skin Epithelial Cells: In vivo Mouse and In vitro Human Study

The size increase of skin epithelial cells during aging is well-known. Here we demonstrate that treatment of aging cells with cytochalasin B substantially decreases cell size. This decrease was demonstrated on a mouse model and on human skin cells in vitro. Six nude mice were treated by topical appl...

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Detalles Bibliográficos
Autores principales: Sokolov, Igor, Guz, Natali V., Iyer, Swaminathan, Hewitt, Amy, Sokolov, Nina A., Erlichman, Joseph S., Woodworth, Craig D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373822/
https://www.ncbi.nlm.nih.gov/pubmed/25807526
http://dx.doi.org/10.1371/journal.pone.0122774