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Zip4 Mediated Zinc Influx Stimulates Insulin Secretion in Pancreatic Beta Cells

Zinc has an important role in normal pancreatic beta cell physiology as it regulates gene transcription, insulin crystallization and secretion, and cell survival. Nevertheless, little is known about how zinc is transported through the plasma membrane of beta cells and which of the class of zinc infl...

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Detalles Bibliográficos
Autores principales: Hardy, Alexandre B., Prentice, Kacey J., Froese, Sean, Liu, Ying, Andrews, Glen K., Wheeler, Michael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373830/
https://www.ncbi.nlm.nih.gov/pubmed/25806541
http://dx.doi.org/10.1371/journal.pone.0119136