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Obesity Alters Gene Expression for GH/IGF-I Axis in Mouse Mammary Fat Pads: Differential Role of Cortistatin and Somatostatin

Locally produced growth hormone (GH) and IGF-I are key factors in the regulation of mammary gland (MG) development and may be important in breast cancer development/progression. Somatostatin (SST) and cortistatin (CORT) regulate GH/IGF-I axis at various levels, but their role in regulating GH/IGF-I...

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Detalles Bibliográficos
Autores principales: Villa-Osaba, Alicia, Gahete, Manuel D., Córdoba-Chacón, José, de Lecea, Luis, Pozo-Salas, Ana I., Delgado-Lista, Francisco Javier, Álvarez-Benito, Marina, López-Miranda, José, Luque, Raúl M., Castaño, Justo P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373840/
https://www.ncbi.nlm.nih.gov/pubmed/25806796
http://dx.doi.org/10.1371/journal.pone.0120955