Histone Deacetylase Inhibition Enhances Tissue Plasminogen Activator Release Capacity in Atherosclerotic Man

The expression of the tissue plasminogen activator (t-PA) gene appears to be under epigenetic control and can be affected by histone deacetylation inhibition. The study aimed to test if histone deacetalyase inhibitor treatment lead to increased t-PA release or reduced exhaustion in t-PA release in r...

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Detalles Bibliográficos
Autores principales: Svennerholm, Kristina, Haney, Michael, Biber, Björn, Ulfhammer, Erik, Saluveer, Ott, Larsson, Pia, Omerovic, Elmir, Jern, Sverker, Bergh, Niklas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373842/
https://www.ncbi.nlm.nih.gov/pubmed/25807501
http://dx.doi.org/10.1371/journal.pone.0121196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373842/
https://www.ncbi.nlm.nih.gov/pubmed/25807501
http://dx.doi.org/10.1371/journal.pone.0121196

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