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Timp3 Deficient Mice Show Resistance to Developing Breast Cancer
Timp3 is commonly silenced in breast cancer, but mechanistic studies have identified both tumor promotion and suppression effects of this gene. We have taken a genetic approach to determine the impact of Timp3 loss on two mouse models of breast cancer. Interestingly, MMTV-PyMT Timp3(−⁄−) mice have d...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373869/ https://www.ncbi.nlm.nih.gov/pubmed/25807548 http://dx.doi.org/10.1371/journal.pone.0120107 |