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Timp3 Deficient Mice Show Resistance to Developing Breast Cancer

Timp3 is commonly silenced in breast cancer, but mechanistic studies have identified both tumor promotion and suppression effects of this gene. We have taken a genetic approach to determine the impact of Timp3 loss on two mouse models of breast cancer. Interestingly, MMTV-PyMT Timp3(−⁄−) mice have d...

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Detalles Bibliográficos
Autores principales:	Jackson, Hartland W., Hojilla, Carlo V., Weiss, Ashley, Sanchez, Otto H., Wood, Geoffrey A., Khokha, Rama
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373869/ https://www.ncbi.nlm.nih.gov/pubmed/25807548 http://dx.doi.org/10.1371/journal.pone.0120107

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