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Endogenously Generated Plasmin at the Vascular Wall Injury Site Amplifies Lysine Binding Site-Dependent Plasminogen Accumulation in Microthrombi

The fibrinolytic system plays a pivotal role in the regulation of hemostasis; however, it remains unclear how and when the system is triggered to induce thrombolysis. Using intra-vital confocal fluorescence microscopy, we investigated the process of plasminogen binding to laser-induced platelet-rich...

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Detalles Bibliográficos
Autores principales: Brzoska, Tomasz, Tanaka-Murakami, Aki, Suzuki, Yuko, Sano, Hideto, Kanayama, Naohiro, Urano, Tetsumei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373877/
https://www.ncbi.nlm.nih.gov/pubmed/25806939
http://dx.doi.org/10.1371/journal.pone.0122196