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Endogenously Generated Plasmin at the Vascular Wall Injury Site Amplifies Lysine Binding Site-Dependent Plasminogen Accumulation in Microthrombi
The fibrinolytic system plays a pivotal role in the regulation of hemostasis; however, it remains unclear how and when the system is triggered to induce thrombolysis. Using intra-vital confocal fluorescence microscopy, we investigated the process of plasminogen binding to laser-induced platelet-rich...
Autores principales: | Brzoska, Tomasz, Tanaka-Murakami, Aki, Suzuki, Yuko, Sano, Hideto, Kanayama, Naohiro, Urano, Tetsumei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373877/ https://www.ncbi.nlm.nih.gov/pubmed/25806939 http://dx.doi.org/10.1371/journal.pone.0122196 |
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