Angiotensin II-Induced Arterial Thickening, Fibrosis and Stiffening Involves Elevated Arginase Function

BACKGROUND: Arterial stiffness (AS) is an independent risk factor for cardiovascular morbidity/mortality. Smooth muscle cell (SMC) proliferation and increased collagen synthesis are key features in development of AS. Arginase (ARG), an enzyme implicated in many cardiovascular diseases, can compete w...

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Detalles Bibliográficos
Autores principales: Bhatta, Anil, Yao, Lin, Toque, Haroldo A., Shatanawi, Alia, Xu, Zhimin, Caldwell, Ruth B., Caldwell, R. William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373900/
https://www.ncbi.nlm.nih.gov/pubmed/25807386
http://dx.doi.org/10.1371/journal.pone.0121727

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373900/
https://www.ncbi.nlm.nih.gov/pubmed/25807386
http://dx.doi.org/10.1371/journal.pone.0121727

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