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The Type 3 Adenylyl Cyclase Is Required for the Survival and Maturation of Newly Generated Granule Cells in the Olfactory Bulb

The type 3 adenylyl cyclase (AC3) is localized to olfactory cilia in the main olfactory epithelium (MOE) and primary cilia in the adult mouse brain. Although AC3 has been strongly implicated in odor perception and olfactory sensory neuron (OSN) targeting, its role in granule cells (GCs), the most ab...

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Detalles Bibliográficos
Autores principales: Luo, Jie, Chen, Xuanmao, Pan, Yung-Wei, Lu, Song, Xia, Zhengui, Storm, Daniel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373939/
https://www.ncbi.nlm.nih.gov/pubmed/25807252
http://dx.doi.org/10.1371/journal.pone.0122057