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Stromal Transcriptional Profiles Reveal Hierarchies of Anatomical Site, Serum Response and Disease and Identify Disease Specific Pathways

Synovial fibroblasts in persistent inflammatory arthritis have been suggested to have parallels with cancer growth and wound healing, both of which involve a stereotypical serum response programme. We tested the hypothesis that a serum response programme can be used to classify diseased tissues, and...

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Detalles Bibliográficos
Autores principales: Filer, Andrew, Antczak, Philipp, Parsonage, Greg N., Legault, Holly M., O’Toole, Margot, Pearson, Mark J., Thomas, Andrew M., Scheel-Toellner, Dagmar, Raza, Karim, Buckley, Christopher D., Falciani, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373951/
https://www.ncbi.nlm.nih.gov/pubmed/25807374
http://dx.doi.org/10.1371/journal.pone.0120917