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Innate Immunity Drives the Initiation of a Murine Model of Primary Biliary Cirrhosis

Invariant natural killer T (iNKT) cells play complex roles in bridging innate and adaptive immunity by engaging with glycolipid antigens presented by CD1d. Our earlier work suggested that iNKT cells were involved in the initiation of the original loss of tolerance in primary biliary cirrhosis (PBC)....

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Detalles Bibliográficos
Autores principales: Chang, Chao-Hsuan, Chen, Ying-Chun, Zhang, Weici, Leung, Patrick S. C., Gershwin, M. Eric, Chuang, Ya-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373957/
https://www.ncbi.nlm.nih.gov/pubmed/25807531
http://dx.doi.org/10.1371/journal.pone.0121320