Synthesis and biological activity of α-glucosyl C24:0 and C20:2 ceramides

α-Glucosyl ceramides 4 and 5 have been synthesised and evaluated for their ability to stimulate the activation and expansion of human iNKT cells. The key challenge in the synthesis of both target molecules was the stereoselective synthesis of the α-glycosidic linkage. Of the methods examined, glycos...

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Detalles Bibliográficos
Autores principales: Jervis, Peter J., Veerapen, Natacha, Bricard, Gabriel, Cox, Liam R., Porcelli, Steven A., Besra, Gurdyal S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374101/
https://www.ncbi.nlm.nih.gov/pubmed/20529677
http://dx.doi.org/10.1016/j.bmcl.2010.05.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374101/
https://www.ncbi.nlm.nih.gov/pubmed/20529677
http://dx.doi.org/10.1016/j.bmcl.2010.05.010

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