RGS1 regulates myeloid cell accumulation in atherosclerosis and aortic aneurysm rupture through altered chemokine signalling

Chemokine signalling drives monocyte recruitment in atherosclerosis and aortic aneurysms. The mechanisms that lead to retention and accumulation of macrophages in the vascular wall remain unclear. Regulator of G-Protein Signalling-1 (RGS1) deactivates G-protein signalling, reducing the response to s...

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Detalles Bibliográficos
Autores principales: Patel, Jyoti, McNeill, Eileen, Douglas, Gillian, Hale, Ashley B., de Bono, Joseph, Lee, Regent, Iqbal, Asif J., Regan-Komito, Daniel, Stylianou, Elena, Greaves, David R., Channon, Keith M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374153/
https://www.ncbi.nlm.nih.gov/pubmed/25782711
http://dx.doi.org/10.1038/ncomms7614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374153/
https://www.ncbi.nlm.nih.gov/pubmed/25782711
http://dx.doi.org/10.1038/ncomms7614

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