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TOPBP1 recruits TOP2A to ultra-fine anaphase bridges to aid in their resolution
During mitosis, sister chromatids must be faithfully segregated to ensure that daughter cells receive one copy of each chromosome. However, following replication they often remain entangled. Topoisomerase IIα (TOP2A) has been proposed to resolve such entanglements, but the mechanisms governing TOP2A...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374157/ https://www.ncbi.nlm.nih.gov/pubmed/25762097 http://dx.doi.org/10.1038/ncomms7572 |