Decoding the Regulatory Network for Blood Development from Single-Cell Gene Expression Measurements

Here we report the use of diffusion maps and network synthesis from state transition graphs to better understand developmental pathways from single cell gene expression profiling. We map the progression of mesoderm towards blood in the mouse by single-cell expression analysis of 3,934 cells, capturi...

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Detalles Bibliográficos
Autores principales: Moignard, Victoria, Woodhouse, Steven, Haghverdi, Laleh, Lilly, Andrew J., Tanaka, Yosuke, Wilkinson, Adam C., Buettner, Florian, Macaulay, Iain C., Jawaid, Wajid, Diamanti, Evangelia, Nishikawa, Shin-Ichi, Piterman, Nir, Kouskoff, Valerie, Theis, Fabian J., Fisher, Jasmin, Göttgens, Berthold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374163/
https://www.ncbi.nlm.nih.gov/pubmed/25664528
http://dx.doi.org/10.1038/nbt.3154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374163/
https://www.ncbi.nlm.nih.gov/pubmed/25664528
http://dx.doi.org/10.1038/nbt.3154

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