Cargando…

Integrated genome and transcriptome sequencing from the same cell

Single-cell genomics and single-cell transcriptomics have recently emerged as powerful tools to study the biology of single cells at a genome-wide scale. However, a major challenge is to quantify both genomic DNA and mRNA from the same cell, which would allow direct comparison of genomic variation a...

Descripción completa

Detalles Bibliográficos
Autores principales: Dey, Siddharth S., Kester, Lennart, Spanjaard, Bastiaan, Bienko, Magda, van Oudenaarden, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374170/
https://www.ncbi.nlm.nih.gov/pubmed/25599178
http://dx.doi.org/10.1038/nbt.3129