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Integrated genome and transcriptome sequencing from the same cell
Single-cell genomics and single-cell transcriptomics have recently emerged as powerful tools to study the biology of single cells at a genome-wide scale. However, a major challenge is to quantify both genomic DNA and mRNA from the same cell, which would allow direct comparison of genomic variation a...
Autores principales: | Dey, Siddharth S., Kester, Lennart, Spanjaard, Bastiaan, Bienko, Magda, van Oudenaarden, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374170/ https://www.ncbi.nlm.nih.gov/pubmed/25599178 http://dx.doi.org/10.1038/nbt.3129 |
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