Lazarillo-related Lipocalins confer long-term protection against type I Spinocerebellar Ataxia degeneration contributing to optimize selective autophagy

BACKGROUND: A diverse set of neurodegenerative disorders are caused by abnormal extensions of polyglutamine (poly-Q) stretches in various, functionally unrelated proteins. A common feature of these diseases is altered proteostasis. Autophagy induction is part of the endogenous response to poly-Q pro...

Descripción completa

Detalles Bibliográficos
Autores principales: del Caño-Espinel, Manuela, Acebes, Judith R, Sanchez, Diego, Ganfornina, Maria D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374295/
https://www.ncbi.nlm.nih.gov/pubmed/25888134
http://dx.doi.org/10.1186/s13024-015-0009-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374295/
https://www.ncbi.nlm.nih.gov/pubmed/25888134
http://dx.doi.org/10.1186/s13024-015-0009-8

Ejemplares similares